'Lorenzo's Oil' breakthrough: Newfound mechanism could prevent or treat deadly peroxisome diseases
'Lorenzo's Oil' breakthrough: Newfound mechanism could prevent or treat deadly peroxisome diseases
Medical researchers have made a major breakthrough in understanding a group of deadly disorders that includes the disease made famous in the movie "Lorenzo's Oil."
Before or after birth, gene linked to mental health has different effects
Scientists have long eyed mutations in a gene known as DISC1 as a possible contributor to schizophrenia and mood disorders, including depression and bipolar disorder. Now, new research suggests that perturbing this gene during prenatal periods, postnatal periods or both may have different effects in mice, leading to separate types of brain alterations and behaviors with resemblance to schizophrenia or mood disorders.
Biologists develop efficient genetic modification of human embryonic stem cells
Biologists have developed an efficient way to genetically modify human embryonic stem cells. Their approach, which uses bacterial artificial chromosomes to swap in defective copies of genes, will make possible the rapid development of stem cell lines that can both serve as models for human genetic diseases and as testbeds on which to screen potential treatments, they say.
Sickle Cell Study Boosts Call For Improved Childhood Immunization Programs In Africa
Children in Africa with sickle cell anemia are dying unnecessarily from bacterial infections, suggests the largest study of its kind. The study has prompted calls for all children in Africa to receive vaccinations against the most common bacterial infections.
Medical researchers have made a major breakthrough in understanding a group of deadly disorders that includes the disease made famous in the movie "Lorenzo's Oil."
Before or after birth, gene linked to mental health has different effects
Scientists have long eyed mutations in a gene known as DISC1 as a possible contributor to schizophrenia and mood disorders, including depression and bipolar disorder. Now, new research suggests that perturbing this gene during prenatal periods, postnatal periods or both may have different effects in mice, leading to separate types of brain alterations and behaviors with resemblance to schizophrenia or mood disorders.
Biologists develop efficient genetic modification of human embryonic stem cells
Biologists have developed an efficient way to genetically modify human embryonic stem cells. Their approach, which uses bacterial artificial chromosomes to swap in defective copies of genes, will make possible the rapid development of stem cell lines that can both serve as models for human genetic diseases and as testbeds on which to screen potential treatments, they say.
Sickle Cell Study Boosts Call For Improved Childhood Immunization Programs In Africa
Children in Africa with sickle cell anemia are dying unnecessarily from bacterial infections, suggests the largest study of its kind. The study has prompted calls for all children in Africa to receive vaccinations against the most common bacterial infections.
